Introduction
Ubrelvy (ubrogepant) is a prescription medication used to treat migraine headaches. It belongs to a class of drugs known as CGRP receptor antagonists, which work by blocking the activity of calcitonin gene-related peptide (CGRP), a chemical messenger in the brain that plays an important role in migraine headache pain. In this article, we’ll explore how Ubrelvy works, including the clinical studies, potential side effects, interactions with other medications, benefits of taking it, dosage guidelines and alternatives.
Clinical Studies of Ubrelvy
Ubrelvy was approved for use in adults in December 2019 after two Phase 3 clinical studies demonstrated its effectiveness in treating migraine headaches. The first study, called ACHIEVE I, included more than 1,000 participants who took either Ubrelvy or placebo. The results showed that those who took Ubrelvy had significantly greater relief from their migraine headache pain within two hours compared to those who took the placebo.
The second study, called ACHIEVE II, included over 1,400 participants who were given either Ubrelvy or placebo. This study showed similar results to ACHIEVE I – those who took Ubrelvy experienced significant relief from their migraine headache pain within two hours compared to those who took the placebo.
Safety & Side Effects
Ubrelvy is generally considered safe and well-tolerated when taken as directed. The most common side effects reported in clinical studies include nausea, dry mouth, and sleepiness. While these side effects are usually mild and go away on their own, they can be serious in some cases. If you experience any severe or persistent side effects while taking Ubrelvy, it’s important to contact your doctor immediately.
Interactions with Other Medications
Ubrelvy can interact with certain medications, including antidepressants and anticonvulsants. It’s important to tell your doctor about all medications you’re taking before starting Ubrelvy, as some medications may increase the risk of side effects or make Ubrelvy less effective. Your doctor can help you determine whether it’s safe to take Ubrelvy with your other medications.
Benefits of Taking Ubrelvy
In addition to providing relief from migraine headache pain, Ubrelvy has been shown to reduce the frequency of migraine attacks. In clinical studies, participants who took Ubrelvy experienced an average of one fewer migraine attack per month compared to those who took the placebo. This can be beneficial for people who suffer from frequent migraines, as it can help reduce the overall number of attacks they experience.
Dosage Guidelines
Ubrelvy is available in tablet form and should be taken orally with water. The recommended dose is one tablet taken as soon as possible after the onset of a migraine attack. It can be taken with or without food. If your migraine headache does not resolve after taking one tablet, you can take a second tablet two hours after the first. Do not take more than two tablets in a 24-hour period.
Alternatives to Ubrelvy
If Ubrelvy is not right for you, there are several other medications that can be used to treat migraine headaches. These include triptans, nonsteroidal anti-inflammatory drugs (NSAIDs), and serotonin receptor agonists. Each of these medications works differently and has its own unique side effects and risks, so it’s important to talk to your doctor about which one is right for you.
Conclusion
Ubrelvy is a prescription medication used to treat migraine headaches. Clinical studies have shown that it is effective in providing relief from migraine headache pain within two hours. It is generally safe and well-tolerated, although it can interact with certain medications and cause side effects in some cases. There are also dosage guidelines that should be followed to ensure the best results. Finally, there are several alternatives to Ubrelvy that can be used to treat migraine headaches.
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